FADS2_RAT Q9Z122
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UniProt:Q9Z122
Recommended name：Acyl-CoA 6-desaturase Curated
EC number：EC:1.14.19.3
Alternative names：Delta(6) fatty acid desaturase (D6D By Similarity; Delta(6) desaturase; Delta-6 desaturase 2 Publications) Fatty acid desaturase 2
Cleaved into：
GeneID：83512
Gene names (primary )：Fads2
Gene names (synonym )：Fadsd6
Gene names (ORF )：
Length：444
Mass：52,380
Sequence：MGKGGNQGEGSTELQAPMPTFRWEEIQKHNLRTDRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESIAWFILSYFGNGWIPTVITAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHIVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLHVFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIRRRDWVDLAWAISYYARFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMNHIVMEIDLDHYRDWFSSQLAATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIVSSLKKSGELWLDAYLHK
Tissue specificity：Expressed in the liver and brain (at protein level) (PubMed:11988075). Highest activity is found in the liver and adrenals followed by the testes and other organs, absent in adipose tissue (PubMed:5094766). 2 s
Induction：
Developmental stage：Inhibited by a shortage of insulin and an increase of glucagon. 1
Protein families：fatty acid desaturase type 1 family