S26A5_RAT Q9EPH0
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UniProt:Q9EPH0
Recommended name：Prestin 1 Publication
EC number：
Alternative names：
Cleaved into：
GeneID：83819
Gene names (primary )：Slc26a5
Gene names (synonym )：Pres
Gene names (ORF )：
Length：744
Mass：81,279
Sequence：MDHAEENEIPAETQKYLVERPIFSHPVLQERLHVKDKVTDSIGDKLKQAFTCTPKKVRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYTVLGQLPDTDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSSALKRKTGVNPAIIMGARRKAMRKYAKEVGNANIANATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEELQRFLPQGENIHTVILDFTQVNFMDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTSNRFFENPALKELLFHSIHDAVLGSQVREAMAEQETTVLPPQEDMEPNATPTTPEA
Tissue specificity：Specifically expressed in outer hair cells of cochleae (PubMed:11125015, PubMed:12782792) (at protein level) (PubMed:11867734). Not detected in other cells of the organ of Corti (PubMed:11125015). 3 s
Induction：Expressed in the outer hair cells in the cochlea from day 7 onwards, including at day 12, at the onset of hearing in rats (at protein level) (PubMed:11867734). Low levels are present in newborn rats and up to day 6. Subsequently, levels increase strongly. Adult levels are detected starting from day 9 in the basal turn of the cochlea, from day 10-11 in the middle turn, and from day 12 in the apical turn 1 Publication
Developmental stage：Up-regulated in cochlea by thyroid hormone T3, perhaps acting via thyroid hormone receptor (at protein level). 1
Protein families：SLC26A/SulP transporter (TC 2.A.53) family