GIMA5_RAT   Q8K3L6


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UniProt:Q8K3L6

Recommended name:GTPase IMAP family member 5

EC number:

Alternative names:

Cleaved into:

GeneID:

Gene names  (primary ):Gimap5

Gene names  (synonym ):Ian4 3 Publications, Ian4l1 1 Publication, Iddm1, Lyp

Gene names  (ORF ):

Length:326

Mass:37,266

Sequence:MEDHGFEELSTRTHDLNVRRLTKGNINFLLSTGQETYSVEDSGLLRILLVGKSGCGKSATGNSILRRPAFESRLRGQSVTRTSQAEMGTWEGRSFLVVDTPPIFESKIQNQDMDKDIGNCYLMCAPGPHVLLLVTQLGRYTVEDAMAVRMVKQIFGVGVMRYMIVLFTHKEDLADESLEEFVTHTGNLDLHRLVQECGRRYCAFNNKASGEEQQGQLAELMALVRRLEQEHEGSFHSNDLFVYTQVFLRGGYSEHQEPYKFYLTKVRQEVEKQKRELEEQEGSWMAKMLCRVTSCLDWHIAVSVLLIVLGLTLLITLINMYIGRWK

Tissue specificity:Primarily expressed in spleen, heart, lung and intestine and, at lower levels, in kidney, stomach and muscle (PubMed:12031988). Expressed in thymus and lymph nodes (at protein level) (PubMed:12031988, PubMed:12930893, PubMed:21487483). In the spleen, expressed in periarteriolar lymphatic sheets (PubMed:12031988). Isoform 2: Expressed at higher levels in T lymphocytes compared to isoform 1 (PubMed:28223986). 4 s

Induction:

Developmental stage:Down-regulated during T lymphocyte activation. 1

Protein families:


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