SERC5_RAT Q63175
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UniProt:Q63175
Recommended name:Serine incorporator 5
EC number:
Alternative names:
Cleaved into:
GeneID:
Gene names (primary ):Serinc5
Gene names (synonym ):Tpo1 1 Publication
Gene names (ORF ):
Length:460
Mass:51,856
Sequence:MSARCCAGQLACCCGSAGCALCCGCCPKFRQSRSTRFMYLFYFTLVIIPCCVMMSPSVMKQMTEHIPFFEDFCKGIKAGDTCENLVGYSAVYRVCFGMACFFFVFCVLTFKVNNSKSCRASIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNVWRYVGAVGSFFFICIQLLLIVEFAHKWNKNWTAGTVRNKLWYASLSLALIMYSIAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLAAISPCVQNRQPHSGLLQPGLISCYVTYLTFSALTSKPEKVVKDEHGKNVTICVPDFGQDFRRDESMVTWLGTLLLVVCISYSCLTSTTRSSSDALQRRYGAPELEVARCCFCFGPDGEDTEEQQNVKEGPRVIYDEKKGTVYSYSYFHFVLLLASLYVMMTLTSWFHYENATIETFFVGSWSIFWVKMASCWMCVLLYLWTLVAPLCCPSRQFSV
Tissue specificity:Brain. Expressed at high levels in the white matter and the oligodendroglial cells of the brain. Expressed at low levels in the liver. 2 s
Induction:First detected in significant amounts at postnatal day 2 (P2) and increases about twofold to a peak value at P17-P20 and declines significantly thereafter. 1 Publication
Developmental stage:Up-regulated during the differentiation of oligodendrocyte lineage cells and during brain development at the time of myelination. Down-regulated in the hippocampal CA fields and dentate gyrus by seizures. 2 s
Protein families: