5HT4R_RAT Q62758
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UniProt:Q62758
Recommended name:5-hydroxytryptamine receptor 4
EC number:
Alternative names:Serotonin receptor 4
Cleaved into:
GeneID:
Gene names (primary ):Htr4
Gene names (synonym ):
Gene names (ORF ):
Length:406
Mass:46,107
Sequence:MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSNSTFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
Tissue specificity:In brain, isoform 5-HT4S is restricted to the striatum (PubMed:7796807). In peripheral tissues, differential expression is also observed in the atrium of the heart where only isoform 5-HT4S is detectable (PubMed:7796807). 1
Induction:
Developmental stage:In brain, isoform 5-HT4L is expressed throughout the brain, except in the cerebellum. 1
Protein families:G-protein coupled receptor 1 family