TENR_RAT Q05546
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UniProt:Q05546
Recommended name：Tenascin-R
EC number：
Alternative names：Janusin Neural recognition molecule J1-160/180 Restrictin
Cleaved into：
GeneID：
Gene names (primary )：Tnr
Gene names (synonym )：
Gene names (ORF )：
Length：1,356
Mass：149,371
Sequence：MGIEGETVVLKNMLIGVNLILLGSMLKPSECRLEVTTERVQRQTVEEEGGASSYNTSSKEQPMVFNHVYNINVPLESLCSSGLEASAEQDVSAEDDTLAEYTGQTSDHESQVTFTHKINLPKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNTNCCQESAATGQLDYVPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGQCANGTCLCQEGYAGEDCSQRRCLNACSGRGHCQEGLCICEEGYQGPDCSAVTPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPSLGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFTPKNNEGGVIAQLPSDVTSFNQTGLKPGEEYIVNVVALKEQARGPPTSASVSTVIDGPTQILVRDVSDTVAFVEWTPPRAKVDFILLKYGLVGGEGGKTTFRLQPPLSQYSVQALRPGSRYEVSISAVRGTNESDASSTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTLTDLVPGTEYGVGISAVMNSKQSIPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGISSEVTVPRDRTSYTLTDLEPGAEYIISITAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVLLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKNITISNVTKDSLTVSWSPPVAPFDYYEYPIDHPSGRLDSSVVPNTVTEFTITRLYPASQYEISLNSVRGREESERICTLVHTAMDSPMDLIATNITPTEALLQWKAPMGEVENYVIVLTHFAMAGETILVDGVSEEFQLVDLLPRTHYTVTMYATSGPLVSGTIATNFSTLLDPPANLTASEVTRQSALISWQPPRAAIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLSENTDYTVLLQAAQEATRSSLTSTIFTTGGRVFSHPQDCAQHLMNGDTLSGVYTIFLNGELSHKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLDNYHRITAQGRYELRVDMRDGQEAVFAYYDKFAVEDSRSLYKLRIGGYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMRPYIHRLTAGRKRRALKF
Tissue specificity：Brain-specific (PubMed:7679676). Expressed in oligodendrocytes and small subsets of neurons (mainly interneurons and motoneurons) of the cerebellum, hippocampus and olfactory bulb (PubMed:7679676). Expressed in dorsal root ganglia (PubMed:28270793). 2 s
Induction：Expression in oligodendrocytes is highest between the second and third postnatal week and low in the adult. In contrast the expression in neurons increases from birth to third postnatal week and is continuous from late development to adulthood. Isoform 1 is the dominant form early in development. Isoform 2 is more prominent later in development and in adulthood. 2 Publications
Developmental stage：Transiently increased in dorsal root ganglia 1 day post-dorsal rhizotomy, returning to comparable levels 3 days post-injury (PubMed:28270793). Increased in dorsal root ganglia in response to both sciatic nerve crush and transection injury (PubMed:28270793). 1
Protein families：tenascin family