LRP2_RAT   P98158


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UniProt:P98158

Recommended name:Low-density lipoprotein receptor-related protein 2

EC number:

Alternative names:Glycoprotein 330 1 Publication (gp330 1 Publication) Megalin

Cleaved into:

GeneID:29216

Gene names  (primary ):Lrp2

Gene names  (synonym ):

Gene names  (ORF ):

Length:

Mass:

Sequence:

Tissue specificity:In the inner ear, expressed in the lumen of the endolymphatic sac where it localizes to macrophage-like cells as well as to mitochondria-rich and ribosome-rich epithelial cells (at protein level) (PubMed:17063000). In the inner ear, expressed in marginal cells of the stria vascularis, epithelial cells at the spiral prominence, epithelial cells of Reissner's membrane facing the cochlear duct, and Kolliker's organ (at protein level) (PubMed:19202329). Expressed in the choroid plexus epithelium in the brain (at protein level) (PubMed:17324488). In the brain, also expressed in astrocytes (at protein level) (PubMed:18466341). Expression also detected in epithelial cells of the kidney glomerulus and proximal tubule, lung, epididymis and yolk sac (PubMed:7510321). 5 s

Induction:

Developmental stage:In the brain, expression is high after birth and gradually decreases from postnatal day 4 until the end of the first postnatal week. 1

Protein families:


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