IMA5_RAT   P83953


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UniProt:P83953

Recommended name:Importin subunit alpha-5

EC number:

Alternative names:

Cleaved into:

GeneID:

Gene names  (primary ):Kpna1

Gene names  (synonym ):

Gene names  (ORF ):

Length:538

Mass:60,137

Sequence:MSTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMTEMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGSQL

Tissue specificity:Expressed significantly in the heart, kidney, placenta, pancreas and spleen with lower levels detected in the brain, liver and skeletal muscle. 1

Induction:

Developmental stage:Injection of 6-hydroxydopamine into the ascending medial forebrain bundle causes the formation of lesions and leads to up-regulation of KPNA1 in the denervated striatum in a time-dependent manner, reaching a maximum two weeks post-lesion. 1

Protein families:


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