KCNB1_RAT P15387
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UniProt:P15387
Recommended name：Potassium voltage-gated channel subfamily B member 1 By Similarity
EC number：
Alternative names：
Cleaved into：
GeneID：25736
Gene names (primary )：Kcnb1
Gene names (synonym )：
Gene names (ORF )：
Length：857
Mass：95,637
Sequence：MPAGMTKHGSRSTSSLPPEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLQVCDDYSLEDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNMKDAFARSIEMMDIVVEKNGESIAKKDKVQDNHLSPNKWKWTKRALSETSSSKSFETKEQGSPEKARSSSSPQHLNVQQLEDMYSKMAKTQSQPILNTKEMAPQSKPPEELEMSSMPSPVAPLPARTEGVIDMRSMSSIDSFISCATDFPEATRFSHSPLASLSSKAGSSTAPEVGWRGALGASGGRLTETNPIPETSRSGFFVESPRSSMKTNNPLKLRALKVNFVEGDPTPLLPSLGLYHDPLRNRGGAAAAVAGLECASLLDKPVLSPESSIYTTASARTPPRSPEKHTAIAFNFEAGVHHYIDTDTDDEGQLLYSVDSSPPKSLHGSTSPKFSTGARTEKNHFESSPLPTSPKFLRPNCVYSSEGLTGKGPGAQEKCKLENHTPPDVHMLPGGGAHGSTRDQSI
Tissue specificity：Expressed in brain (PubMed:12954870, PubMed:1740690, PubMed:1961744, PubMed:7623158, PubMed:8508921). Expressed in the hippocampus, cerebral cortex, cerebellum, thalamus, hypothalamus, olfactory bulb, corpus striatum and medial hebenula (PubMed:10414301, PubMed:16319318, PubMed:8463836). Expressed in pancreatic islets (PubMed:12403834). Expressed in heart and skeletal muscle (PubMed:10414301, PubMed:1740690, PubMed:19219384). Levels remain constant throughout postnatal development (PubMed:17192433). Expressed in neocortical pyramidal neurons and inhibitory interneurons (PubMed:10618149, PubMed:12832499, PubMed:17192433, PubMed:17379638, PubMed:19014551, PubMed:1961744, PubMed:20202934, PubMed:24477962, PubMed:9522360). Expressed in the superior cervical ganglion (SCG) neurons (PubMed:12451110). Expressed in globus pallidus neurons (PubMed:10414968). Expressed in pancreatic beta cells (PubMed:11463864, PubMed:22411134). Expressed in cardiomyocytes (PubMed:17965280). Expressed in arterial smooth muscle, alveolar epithelium and parenchyma (at protein level) (PubMed:15322114, PubMed:9362476, PubMed:9616203). Expressed in brain, heart, lung, liver, colon, kidney and adrenal gland (PubMed:19074135, PubMed:8508921, PubMed:9362476). Expressed in pyramidal cells of the cerebral cortex, in Purkinje and granule cells of the cerebellum (PubMed:8463836). Expressed in CA1-CA3 pyramidal cells, dentate granule cells and interneurons of the hippocampus (PubMed:10024359, PubMed:7623158). Expressed in pulmonary artery (PA) smooth muscle cells (PubMed:9362476). 27 s
Induction：Expressed in embryonic brain at 14 dpc, and thereafter (at protein level) (PubMed:8508921). Expressed in embryonic brain at 14 dpc, and thereafter (PubMed:8508921). 1 Publication
Developmental stage：Down-regulated by angiotensin II in a NFATC3-dependent manner (PubMed:15322114). 1
Protein families：12560340