S38A3_RAT Q9JHZ9
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UniProt:Q9JHZ9
Recommended name:Sodium-coupled neutral amino acid transporter 3 Curated
EC number:
Alternative names:
Cleaved into:
GeneID:252919
Gene names (primary ):Slc38a3
Gene names (synonym ):Snat3
Gene names (ORF ):
Length:504
Mass:55,637
Sequence:MEIPRQTEMVELVPNGKHLEGLLPVGMPTADTQRAEDAQHCGEGKGFLQQSSSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEKPTPVWYMDGNYLVILVSVIIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLAHNLVNATGNFSHMVVVEEKSQLQSEPDTAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFDVLILCVRVAVLIAVTLTVPIVLFPVRRAIQQMLFQNQEFSWLRHVLIATGLLTCINLLVIFAPNILGIFGIIGATSAPCLIFIFPAIFYFRIMPTEKEPVRSTPKILALCFAAVGFLLMTMSLSFIITDWVSGTSQHGGNH
Tissue specificity:Highly expressed in liver (PubMed:10619430). Expressed in skeletal muscle. Expressed in kidney, heart and brain (PubMed:10619430). Not detected in gut, lung or spleen (PubMed:10619430). Expressed ubiquitously in hepatocytes in liver whereas in kidney expression is restricted to the medulla (PubMed:10619430). Within brain, expressed in glial cells (PubMed:10619430). In the cerebellum, expressed on Bergmann glial fibers in the molecular layer and astrocytes in the granule layer (PubMed:10619430). Expressed in brain kidney and liver (at protein level) (PubMed:15716335). In the adult kidney, highly expressed in the outer strip of the outer medulla and medullary rays penetrating into the kidney cortex (at protein level) (PubMed:15716335). 3 s
Induction:
Developmental stage:Induced by chronic metabolic acidosis (CMA). 1
Protein families: