S4A10_RAT Q80ZA5
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UniProt:Q80ZA5
Recommended name：Sodium-driven chloride bicarbonate exchanger 1 Publication
EC number：
Alternative names：
Cleaved into：
GeneID：
Gene names (primary )：Slc4a10
Gene names (synonym )：Ncbe 1 Publication
Gene names (ORF )：
Length：1,117
Mass：125,639
Sequence：MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGGESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQSQKKLTNRIPIVRSFADIGKKQSEPNSMDKNGQVVSPQSAPACAENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRLDKGPPHQQEREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKTPSLPNGTAAHGGPEQHGGHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSESYPINMHNDLELLTQYSCNCMEPHSPSNDTLKEWRESNISASDIIWGNLTVSECRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEDEGTVQLPLEGHYRDDPSVINISDEMSKTAMWGNLLVTADNSKEKESRFPSKSSPS
Tissue specificity：In the brain, detected in cerebral cortex, subcortex, cerebellum, hippocampus and medulla (at protein level) (PubMed:18061361). Expressed in neurons but not in astrocytes (at protein level) (PubMed:18061361). Isoforms starting with Met-Glu-Ile-Lys are found predominantly in the brain with lower levels in the eye while isoforms starting with Met-Cys-Asp-Leu are most abundant in the kidney with lower levels in the duodenum, jejunum and ileum (at protein level) (PubMed:23409100). In the kidney, isoforms starting with Met-Cys-Asp-Leu are primarily expressed in the cortex, the outer stripe of the outer medulla and the inner stripe of the outer medulla (ISOM) but are not detectable in the inner medulla (IM) while isoforms starting with Met-Glu-Ile-Lys are predominantly expressed in the ISOM and IM (PubMed:28280139). Expressed in the brain, in the hippocampus as well as in dentate gyrus, cortical layers, cerebellum, olfactory bulb and in the epithelial cells of the choroid plexus. Detected in pituitary, testis, kidney and ileum. Detected also in spleen and lung 6 s
Induction：Expressed in spinal cord and brain at 19 dpc through adulthood. 1 Publication
Developmental stage：Mainly expressed in the jejenum (at protein level). 1
Protein families：anion exchanger (TC 2.A.31) family