DUS1_RAT Q64623
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UniProt:Q64623
Recommended name：Dual specificity protein phosphatase 1 Curated
EC number：EC:3.1.3.16
Alternative names：Mitogen-activated protein kinase phosphatase 1 (MAP kinase phosphatase 1; MKP-1) Protein-tyrosine phosphatase CL100 Imported Protein-tyrosine phosphatase non-receptor type 16
Cleaved into：
GeneID：114856
Gene names (primary )：Dusp1
Gene names (synonym )：Cl100 Imported, Mkp1, Ptpn16
Gene names (ORF )：
Length：367
Mass：39,541
Sequence：MVMEVGILDAGGLRALLRERAAQCLLLDCRSFFAFNAGHIVGSVNVRFSTIVRRRAKGAMGLEHIVPNTELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARSTQVFFLQGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLQSPITTSPSC
Tissue specificity：Brain. High level expression seen in the cingulate gyrus within the retrospinal cortex, ventral and medial divisions of the anterior thalamus and the medial geniculate nucleus. Expressed at moderate levels in the parietal and temporal cortex. Expressed in the cerebellum. 3 s
Induction：
Developmental stage：Exhibits night/day variations with a 100-fold increased expression at night in the pineal gland (at protein level). Up-regulation is due to a large degree to the release of norepinephrine from nerve terminals in the pineal gland and cAMP signaling pathway. 2 s
Protein families：