TESK1_RAT   Q63572


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UniProt:Q63572

Recommended name:Dual specificity testis-specific protein kinase 1

EC number:EC:2.7.12.1

Alternative names:Testicular protein kinase 1

Cleaved into:

GeneID:29460

Gene names  (primary ):Tesk1

Gene names  (synonym ):

Gene names  (ORF ):

Length:628

Mass:67,988

Sequence:MAGERPPLRGPGPGETPVEGPGGAGGGPGRGRPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRREDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQILEQLPEPTPLAKMPLAKAPLTYNQGSVPRGGPSATLPRSDPRLSRSRSDLFLPPSPESPPSWGDNLTRVNPFSLREDLRGGKIKLLDTPCKPATPLPLVPPSPLTSTQLPLVASPESLVQPETPVRRCRSLPSSPELPRRMETALPGPGPSPVGPSTEERMDCEGSSPEPEPPGPAPQLPLAVATDNFISTCSSASQPWSARPGPSLNNNPPAVVVNSPQGWAREPWNRAQHSLPRAAALERTEPSPPPSAPREQEEGLPCPGCCLSPFSFGFLSMCPRPTPAVARYRNLNCEAGSLLCHRGHHAKPPTPSLQLPGARS

Tissue specificity:Weakly expressed in sciatic nerves (at protein level) (PubMed:22302232). Highly expressed in testicular germ cells (PubMed:10207045, PubMed:8537404). Expressed at low levels in brain, lung, heart, liver and kidney (PubMed:10207045). 3 s

Induction:

Developmental stage:Induced by fibronectin-mediated cell adhesion of Schwann cells (PubMed:22302232). Induced by sciatic nerve crush injury, expression peaks 2 weeks post-injury and returns to normal at 4 weeks post-injury in the macrophages of promyelinating Schwann tubules (PubMed:22302232). 1

Protein families:protein kinase superfamily


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