TESK1_RAT Q63572
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UniProt:Q63572
Recommended name:Dual specificity testis-specific protein kinase 1
EC number:EC:2.7.12.1
Alternative names:Testicular protein kinase 1
Cleaved into:
GeneID:29460
Gene names (primary ):Tesk1
Gene names (synonym ):
Gene names (ORF ):
Length:628
Mass:67,988
Sequence:MAGERPPLRGPGPGETPVEGPGGAGGGPGRGRPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRREDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQILEQLPEPTPLAKMPLAKAPLTYNQGSVPRGGPSATLPRSDPRLSRSRSDLFLPPSPESPPSWGDNLTRVNPFSLREDLRGGKIKLLDTPCKPATPLPLVPPSPLTSTQLPLVASPESLVQPETPVRRCRSLPSSPELPRRMETALPGPGPSPVGPSTEERMDCEGSSPEPEPPGPAPQLPLAVATDNFISTCSSASQPWSARPGPSLNNNPPAVVVNSPQGWAREPWNRAQHSLPRAAALERTEPSPPPSAPREQEEGLPCPGCCLSPFSFGFLSMCPRPTPAVARYRNLNCEAGSLLCHRGHHAKPPTPSLQLPGARS
Tissue specificity:Weakly expressed in sciatic nerves (at protein level) (PubMed:22302232). Highly expressed in testicular germ cells (PubMed:10207045, PubMed:8537404). Expressed at low levels in brain, lung, heart, liver and kidney (PubMed:10207045). 3 s
Induction:
Developmental stage:Induced by fibronectin-mediated cell adhesion of Schwann cells (PubMed:22302232). Induced by sciatic nerve crush injury, expression peaks 2 weeks post-injury and returns to normal at 4 weeks post-injury in the macrophages of promyelinating Schwann tubules (PubMed:22302232). 1
Protein families:protein kinase superfamily