I2BPL_RAT   Q5EIC4


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UniProt:Q5EIC4

Recommended name:Probable E3 ubiquitin-protein ligase IRF2BPL By Similarity

EC number:EC:2.3.2.27

Alternative names:Enhanced at puberty protein 1 Interferon regulatory factor 2-binding protein-like Polyglutamine-containing protein

Cleaved into:

GeneID:314329

Gene names  (primary ):Irf2bpl

Gene names  (synonym ):Eap1, Pqcp

Gene names  (ORF ):

Length:783

Mass:81,496

Sequence:MSAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRAHGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAQQQQQQQQQQQQQQQQQPQQLNHVDGSTKPAVLPAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHAARLPNGLGGPNGFPKPAPEEGPPELNRQSPNSSSAATSVASRRGTHSGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPHGLGGSRGPPTPAPPGAPGGPACLGGPPGVSATVSSAPSSTSSTVAEVGVGAAGKRPGSVSSTDQERELKEKQRNAEALAELSESLRNRAEEWANKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKPGMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYEKKHGSGDWRLLGDLLPEAVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPTGRGAAASLRKRKASPEPPDSAESALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGPLCCTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDP

Tissue specificity:Expressed in the regions of the hypothalamus involved in reproductive control, such as medial preoptic area, arcuate nucleus and ventromedial nucleus. 1

Induction:

Developmental stage:Up-regulated during puberty in the hypothalamus, but not in the cerebral cortex. 1

Protein families:


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