AP2A_RAT P58197
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UniProt:P58197
Recommended name:Transcription factor AP-2-alpha
EC number:
Alternative names:AP-2 transcription factor Activating enhancer-binding protein 2-alpha Activator protein 2 (AP-2)
Cleaved into:
GeneID:
Gene names (primary ):Tfap2a
Gene names (synonym ):Tcfap2a
Gene names (ORF ):
Length:437
Mass:47,947
Sequence:MLWKLTDNIKYEDCEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHGLGSGLGDLPIHSLPHAIEDVPHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSSPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVARKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNSAKSSDKEEKHRK
Tissue specificity:In the brain, highly expressed in the hippocampus, hypothalamus and cerebral cortex.
Induction:
Developmental stage:During retinoic acid-mediated differentiation and by nerve growth factor (NGF). Inhibited by the antidepressants, citalopram and imipramin.
Protein families:AP-2 family