ACSL6_RAT P33124
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UniProt:P33124
Recommended name:Long-chain-fatty-acid--CoA ligase 6 Curated
EC number:EC:6.2.1.3
Alternative names:Arachidonate--CoA ligase Curated (EC:6.2.1.15 1 Publication) . EC:6.2.1.15 (UniProtKB | ENZYME | Rhea) 1 Publication Long-chain acyl-CoA synthetase 6 (LACS 6) Long-chain-fatty-acid--CoA ligase, brain isozyme
Cleaved into:
GeneID:
Gene names (primary ):Acsl6
Gene names (synonym ):Acs2, Facl6
Gene names (ORF ):
Length:697
Mass:78,180
Sequence:MQTQEILRILRLPELSDLGQFFRSLSATTLVSMGALAAILAYWLTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGDCTQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPEQPYQWLSYQEVAKRAEFLGSGLLQHDCKVGTEQFIGVFAQNRPEWIIAELACYTYSMVVVPLYDTLGPGSIRYIINTADICTVIVDKPHKAILLLEHVERKETPGLKLVILMEPFDDALRERGKKCGVDIKSMQAIEDSGQENHRVPVPPRPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHFSYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALRPTIFPVVPRLLNRMYDKIFHQADTSLKRWLLEFAAKRKQAEVRSGIIRNNSIWDELFFNKIQASLGGHVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDAEELNYWTSKGEGEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKAFLVGIVVPDPEVMPCWAQKKGIEGNYQELCKSKELKKAILDDMVMLGKESGLHSFEQVKAIYIHCDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSISM
Tissue specificity:Expressed predominantly in brain and, to a much lesser extent, in heart and adrenal.
Induction:
Developmental stage:Isoform 1 is detected 10 days after birth, and increased in a coordinate fashion during the development of brain, and the amount did not decrease when myelination was completed. 1
Protein families: