ACSL1_RAT P18163
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UniProt:P18163
Recommended name:Long-chain-fatty-acid--CoA ligase 1 Curated
EC number:EC:6.2.1.3
Alternative names:Arachidonate--CoA ligase (EC:6.2.1.15 1 Publication) . EC:6.2.1.15 (UniProtKB | ENZYME | Rhea) 1 Publication Long-chain acyl-CoA synthetase 1 (LACS 1) Long-chain-fatty-acid--CoA ligase, liver isozyme Phytanate--CoA ligase (EC:6.2.1.24 2 Publications) . EC:6.2.1.24 (UniProtKB | ENZYME | Rhea) 2 Publications
Cleaved into:
GeneID:25288
Gene names (primary ):Acsl1
Gene names (synonym ):Acs1, Acsl2, Facl2
Gene names (ORF ):
Length:699
Mass:78,179
Sequence:MEVHELFRYFRMPELIDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEVTGTTEGVRRSAVLEDDKLLLYYYDDVRTMYDGFQRGIQVSNDGPCLGSRKPNQPYEWISYKQVAEMAECIGSALIQKGFKPCSEQFIGIFSQNRPEWVTIEQGCFTYSMVVVPLYDTLGTDAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYDNDLVERGQKCGVEIIGLKALEDLGRVNRTKPKPPEPEDLAIICFTSGTTGNPKGAMVTHQNIMNDCSGFIKATESAFIASPEDVLISFLPLAHMFETVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSVKRWLLDFASKRKEAELRSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPCNYIKLVDVEDMNYQAAKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAIVVPDVEILPSWAQKRGFQGSFEELCRNKDINKAILEDMVKLGKNAGLKPFEQVKGIAVHPELFSIDNGLLTPTLKAKRPELRNYFRSQIDELYSTIKI
Tissue specificity:Liver, heart, epididymal adipose and to a lesser extent brain, small intestine and lung.
Induction:Levels remain constant during development.
Developmental stage:By high fat and high carbohydrate diets.
Protein families: