TRIM3_RAT O70277
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UniProt:O70277
Recommended name:Tripartite motif-containing protein 3
EC number:EC:2.3.2.27
Alternative names:Brain-expressed RING finger protein RING finger protein 22
Cleaved into:
GeneID:83616
Gene names (primary ):Trim3
Gene names (synonym ):Berp, Rnf22
Gene names (ORF ):
Length:744
Mass:80,796
Sequence:MAKREDSPGPEVQPMDKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSAVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLESICGAKQKVLQTQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSAAAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELCAEITGPDGMRLAVPVVDHKNGTYELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIVDELVFRVGSRGREKGEFTNLHPLSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
Tissue specificity:Highly expressed in the brain, moderate levels in the lung, very low levels in the liver, kidney and heart. In the brain, expression was highest in the cerebellum. Expression in the brain is found at low levels at embryonic day 15 and then increases during the first two postnatal weeks before decreasing through adulthood (PubMed:20352094). 1
Induction:
Developmental stage:
Protein families:TRIM/RBCC family