ECEL1_RAT   Q9JHL3


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UniProt:Q9JHL3

Recommended name:Endothelin-converting enzyme-like 1

EC number:EC:3.4.24.-

Alternative names:Damage-induced neuronal endopeptidase Xce protein

Cleaved into:

GeneID:60417

Gene names  (primary ):Ecel1

Gene names  (synonym ):Dine, Xce

Gene names  (ORF ):

Length:775

Mass:87,944

Sequence:MEAPYSMTAHYDEFQEVKYESRCGTGGARGTSLPPGFPRSSGRSASGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPGAAGTGGACPEGCPERKAFARAARFLSANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPTGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAADRPGAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEGSEKVLAAYKVFMERLLRLLGADAVEQKAQEILQLEQRLANISVSEYDDLRRDVSSVYNKVTLGQLQKITPHLQWKWLLDQIFQEDFSEEEEVVLLATDYMQQVSQLIRSTPRRILHNYLVWRVVVVLSEHLSPPFREALHELAKEMEGNDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAQTKAAARAKLQYMMVMVGYPDFLLKPEAVDKEYEFEVHEKTYLKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLHKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYYAYQKWVREHGPEHPLHRLKYTHNQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNPVHKCSVW

Tissue specificity:Highly expressed in the CNS, in particular in neurons of the caudate putamen, diagonal band, the paraventricular nucleus of the thalamus, part of the hypothalamus, in cranial motor nuclei, inferior olive, and substantia gelatinosa of the spinal tract trigeminal nucleus. Not detected in cerebral cortex, hippocampus and cerebellum.

Induction:

Developmental stage:By mechanical damage to nerve cells.

Protein families:


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