PTF1A_RAT   Q64305


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UniProt:Q64305

Recommended name:Pancreas transcription factor 1 subunit alpha

EC number:

Alternative names:

Cleaved into:

GeneID:117034

Gene names  (primary ):Ptf1a

Gene names  (synonym ):Ptf1p48

Gene names  (ORF ):

Length:326

Mass:35,305

Sequence:MDAVLLEHFPGALDTFPSSYFDEEDFFTDQSSRDPLEDGDELLGDEQAEVEFLSHQLHEYCYRDGACLLLQPAPSAAPHALAPPPLGDPGEPEDSGSYCCDAGAPLGAFPYSPGSPPSCLAYPCTAVLSPGTRLRGLNGAAAAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGSGTGGCGGPGGSRHLGGDSPGNQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWADEKQLKEQNIIRTAKVWTPEDPRKLNSKSFDNIENEPPFEFVS

Tissue specificity:Exocrine pancreas-specific. Expressed in azaserine-induced pancreatic tumors (at protein level). Expressed in AR42J cells but not in ARIP, DSL6A, or DSL6B cells. Down-regulation is associated with the change of an azaserine-induced acinar cell carcinoma to a ductal phenotype. 1

Induction:

Developmental stage:Expressed from day 12 of gestation in pancreatic structures. 1

Protein families:


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