PJA2_RAT   Q63364


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UniProt:Q63364

Recommended name:E3 ubiquitin-protein ligase Praja-2

EC number:EC:2.3.2.27

Alternative names:Praja2

Cleaved into:

GeneID:192256

Gene names  (primary ):Pja2

Gene names  (synonym ):Neurodap1

Gene names  (ORF ):

Length:707

Mass:77,921

Sequence:MSQYTEKEPSVMDQDSSKAAWPRAAGGYQTITGRRYGRRHAYVSFKPCMTRHERSLGRAGDDYEVLELDDVAKENTAGSSSLDQVHPSLPSETTVEKSETEIPTCGPALNQSTESNPSVATVCHSEEVRETLDSSTNLQNHAERECTPAVCNASSVQNGIVLVHTDSYDPDSKHDENDSLQLCAQAVEGGRRQKVLGNAVFELENGEVERYADLCPSVPSLSGEIREESEELGSALLEKNSAGDAEAVHQDGQEFQRSSEDGIVRKRRQDDTDQGRQTENSTEDADCVPGHVEQNTSERANHHGSSPEQVVRPKVRKVISSSQVDQESGFNRHEAKQRSVQRWREALEVEECSSDDPIIKCDDYDGDHDCMFLTPSYSRVTPREAERHRATAENGATASGRQEARENAFWNACGEYYQLFDKDEDSSECSDGEWSASLPHRFSGTEKDQSSSDESWETLPGKDENEPELQSDSSGPEEENQELSLQEGEQTSLEEGEIPWLQYNEVNESSSDEGNEPANEFAQPEAFMLDGNNNLEDDSSVSEDLDVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDGLPETLVLEDHTAIGQEQCCPICCSEYIKDDIATELPCHHFFHKPCVSIWLQKSGTCPVCRRHFPPAVIDASAAASSEPDLDASPANDNAEEAP

Tissue specificity:Highly expressed in the brain, in nerve cells but not in glial cells. Abundantly expressed in pyramidal neurons and in the CA3 region of apical dendrites. Colocalizes with PRKAR2B in dentate granule cells and at postsynaptic sites of primary hippocampal neurons. 2 s

Induction:

Developmental stage:

Protein families:


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