S22A7_RAT Q5RLM2
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UniProt:Q5RLM2
Recommended name:Solute carrier family 22 member 7 1 Publication
EC number:
Alternative names:
Cleaved into:
GeneID:89776
Gene names (primary ):Slc22a7
Gene names (synonym ):Nlt, Oat2
Gene names (ORF ):
Length:535
Mass:58,654
Sequence:MGFEDLLDKVGGFGPFQLRNLVLMALPRMLLPMHFLLPVFMAAVPAHHCALPGAPANLSHQDLWLEAHLPRETDGSFSSCLRFAYPQTVPNVTLGTEVSNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRRLLLVAYVSSLVLGLMSAASINYIMFVVTRTLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTVFWSGGVLLLALVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLLSCAKLNGRPVGEGSLSQEALNNVVTMERALQRPSYLDLFRTSQLRHISLCCMMVWFGVNFSYYGLTLDVSGLGLNVYQTQLLFGAVELPSKIMVYFLVRRLGRRLTEAGMLLGAALTFGTSLLVSLETKSWITALVVVGKAFSEAAFTTAYLFTSELYPTVLRQTGLGLTALMGRLGASLAPLAALLDGVWLLLPKVAYGGIALVAACTALLLPETKKAQLPETIQDVERKSTQEEDV
Tissue specificity:Expressed in liver and kidney (PubMed:11504818, PubMed:16885152, PubMed:21446918, PubMed:25904762, PubMed:8056831, PubMed:9650585). Expressed at low levels in adipose tissue (PubMed:8056831). Expressed in fetal liver (PubMed:8056831). In kidney, expressed at the brush border of the proximal tubule S3 segment (S3) in the outer stripe and medullary rays (PubMed:16885152, PubMed:25904762). In kidney, expression is higher in female than male (PubMed:16885152). 6 s
Induction:
Developmental stage:Strongly inhibited by androgen, and weakly stimulated by estrogen and progesterone, which results in gender differences (female > male) that appears in puberty, for expression in kidney. 1
Protein families: