S22A7_RAT   Q5RLM2


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UniProt:Q5RLM2

Recommended name:Solute carrier family 22 member 7 1 Publication

EC number:

Alternative names:

Cleaved into:

GeneID:89776

Gene names  (primary ):Slc22a7

Gene names  (synonym ):Nlt, Oat2

Gene names  (ORF ):

Length:535

Mass:58,654

Sequence:MGFEDLLDKVGGFGPFQLRNLVLMALPRMLLPMHFLLPVFMAAVPAHHCALPGAPANLSHQDLWLEAHLPRETDGSFSSCLRFAYPQTVPNVTLGTEVSNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRRLLLVAYVSSLVLGLMSAASINYIMFVVTRTLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTVFWSGGVLLLALVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLLSCAKLNGRPVGEGSLSQEALNNVVTMERALQRPSYLDLFRTSQLRHISLCCMMVWFGVNFSYYGLTLDVSGLGLNVYQTQLLFGAVELPSKIMVYFLVRRLGRRLTEAGMLLGAALTFGTSLLVSLETKSWITALVVVGKAFSEAAFTTAYLFTSELYPTVLRQTGLGLTALMGRLGASLAPLAALLDGVWLLLPKVAYGGIALVAACTALLLPETKKAQLPETIQDVERKSTQEEDV

Tissue specificity:Expressed in liver and kidney (PubMed:11504818, PubMed:16885152, PubMed:21446918, PubMed:25904762, PubMed:8056831, PubMed:9650585). Expressed at low levels in adipose tissue (PubMed:8056831). Expressed in fetal liver (PubMed:8056831). In kidney, expressed at the brush border of the proximal tubule S3 segment (S3) in the outer stripe and medullary rays (PubMed:16885152, PubMed:25904762). In kidney, expression is higher in female than male (PubMed:16885152). 6 s

Induction:

Developmental stage:Strongly inhibited by androgen, and weakly stimulated by estrogen and progesterone, which results in gender differences (female > male) that appears in puberty, for expression in kidney. 1

Protein families:


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