PGH2_RAT P35355
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UniProt:P35355
Recommended name:Prostaglandin G/H synthase 2
EC number:EC:1.14.99.1
Alternative names:Cyclooxygenase-2 (COX-2) PHS II Prostaglandin H2 synthase 2 (PGH synthase 2; PGHS-2) Prostaglandin-endoperoxide synthase 2
Cleaved into:
GeneID:29527
Gene names (primary ):Ptgs2
Gene names (synonym ):Cox-2, Cox2
Gene names (ORF ):
Length:604
Mass:69,164
Sequence:MLFRAVLLCAALALSHAANPCCSNPCQNRGECMSIGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRNSIMRYVLTSRSHLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGTNMMFAFFAQHFTHQFFKTDQKRGPGFTRGLGHGVDLNHVYGETLDRQHKLRLFQDGKLKYQVIGGEVYPPTVKDTQVDMIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYTFKQFLYNNSILLEHGLAHFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYHDIDAMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFRIINTASIQSLICNNVKGCPFASFNVQDPQPTKTATINASASHSRLDDINPTVLIKRRSTEL
Tissue specificity:Expressed throughout the forebrain in discrete populations of neurons and is enriched in the cortex and hippocampus.
Induction:
Developmental stage:By cytokines and mitogens.
Protein families: