GNAT3_RAT P29348
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UniProt:P29348
Recommended name：Guanine nucleotide-binding protein G(t) subunit alpha-3
EC number：
Alternative names：
Cleaved into：
GeneID：286924
Gene names (primary )：Gnat3
Gene names (synonym )：Gnat-3
Gene names (ORF )：
Length：354
Mass：40,294
Sequence：MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVVYSNTLQSILAIVKAMTTLGIDYVNPRSREDQQLLLSMANTLEDGDMTPQLAEIIKRLWGDPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVTKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
Tissue specificity：Expressed in taste buds (sensory organs of clustered epithelial cells) of the circumvallate, foliate and fungiform papillae of the tongue, as well as in nasoincisor, palatal and epiglottal taste buds at protein level. Expressed in enteroendocrine of the gut, in the lumenal pole of a subset of brush cells lining the stomach and the intestine at protein level. Detected in solitary cells throughout the respiratory track. Expressed also in spermatozoa. 6 s
Induction：Expressed in scattered solitary ovoid or bipolar cells among the oral epithelium from day 1-7, but with higher frequency in the soft palate as compared with the nasoincisor, circumvallate, and foliate papillae at day 1. During the second week, the solitary cells could no longer be recognized while cells expressing GNAT3 within the taste buds gradually increased. The onset of taste transduction accomplished by the palatal taste buds developed earlier than that achieved by taste buds in the circumvallate and foliate papillae. 1 Publication
Developmental stage：By bitter compounds denatonium and quinine. 1
Protein families：