MARHB_RAT A6P320
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UniProt:A6P320
Recommended name:E3 ubiquitin-protein ligase MARCHF11
EC number:EC:2.3.2.27
Alternative names:Membrane-associated RING finger protein 11 Membrane-associated RING-CH protein XI (MARCH-XI) RING-type E3 ubiquitin transferase MARCHF11 Curated
Cleaved into:
GeneID:499558
Gene names (primary ):Marchf11
Gene names (synonym ):March11
Gene names (ORF ):
Length:398
Mass:44,085
Sequence:MSDEGSKRGSRADSLEAEPPLPPPPPPPPPGESSLVPTSPRYRPPLPAPLERIVGSGEPPVELAPRRKGEPLPPLPPSRLPGDQEVSAAGDSCEGPRRLPEVKLPEAAAGKGSPAEPEAGACREGERRGTGDQPETRSVYSSRSSSSGGSGDQRSGHQHQHHQPICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVTAIKMKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVHEGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLPLSALRNRNLVHPTQLTSPRFQCGYVLLHLFNRMRAHEDVSEDNGSGEVVMRVTSV
Tissue specificity:Predominantly expressed in testis. Present in early developing spermatids. Not present in spermatogonia, spermatocytes or somatic cells (i.e. peritubular, Leydig, and Sertoli cells). Present in early round spermatids at step 4, remains until step 11, then it decreases at steps 12-15, and diminishes after step 16 (at protein level). Also expressed at lower level in brain. 1
Induction:
Developmental stage:
Protein families: