MARHB_RAT   A6P320


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UniProt:A6P320

Recommended name:E3 ubiquitin-protein ligase MARCHF11

EC number:EC:2.3.2.27

Alternative names:Membrane-associated RING finger protein 11 Membrane-associated RING-CH protein XI (MARCH-XI) RING-type E3 ubiquitin transferase MARCHF11 Curated

Cleaved into:

GeneID:499558

Gene names  (primary ):Marchf11

Gene names  (synonym ):March11

Gene names  (ORF ):

Length:398

Mass:44,085

Sequence:MSDEGSKRGSRADSLEAEPPLPPPPPPPPPGESSLVPTSPRYRPPLPAPLERIVGSGEPPVELAPRRKGEPLPPLPPSRLPGDQEVSAAGDSCEGPRRLPEVKLPEAAAGKGSPAEPEAGACREGERRGTGDQPETRSVYSSRSSSSGGSGDQRSGHQHQHHQPICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVTAIKMKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVHEGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLPLSALRNRNLVHPTQLTSPRFQCGYVLLHLFNRMRAHEDVSEDNGSGEVVMRVTSV

Tissue specificity:Predominantly expressed in testis. Present in early developing spermatids. Not present in spermatogonia, spermatocytes or somatic cells (i.e. peritubular, Leydig, and Sertoli cells). Present in early round spermatids at step 4, remains until step 11, then it decreases at steps 12-15, and diminishes after step 16 (at protein level). Also expressed at lower level in brain. 1

Induction:

Developmental stage:

Protein families:


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