GRIP2_RAT   Q9WTW1


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UniProt:Q9WTW1

Recommended name:Glutamate receptor-interacting protein 2

EC number:

Alternative names:AMPA receptor-interacting protein GRIP2

Cleaved into:

GeneID:

Gene names  (primary ):Grip2

Gene names  (synonym ):

Gene names  (ORF ):

Length:1,043

Mass:112,488

Sequence:MLAVSLKWRLGVVRRRPKDDGPYSKGGKDTAGTDGALVCRRQSIPEEFRGITMVELIKREGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNVGDYIRSVNGIRLTRLRHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIISKTVDVSLYKEGNSFGFVLRGGAHEDLHKSRPLVLTYVRPGGPADREGSLKVGDRLLSIDGIPLHGASHATAIATLQQCSHEALFQVEYDVATPDTVANASGPLVVEIAKTPGSALGISLTTGSHRNKPAITIDRIKPASVVDRSGALHAGDHILAIDGTSTEHCSLVEATKLLASVTEKVRLEILPAPQSRRPLKPPEAVRIQRSEQLHHWDPCVPSCHSPRPSHCRAPTWAPGGQDQSRSVSSTPFSSPTMNPAFPCANASTLPRGPMSPRTTAGRRRQRRKEHRSSLSLASSTVGPGGQIVHTETTEVVLCGDPLSGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLAINGIATEDGTMEEANQLLRDAALARKVVLEIEFDVAESVIPSSGTFHVKLPKRRGVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDHCPMEYAVQILRQCEDLVKLKIRKDEDNSDEQESSGAVSYTVELKRYGGPLGITISGTEEPFDPIIISGLTKRGLAERTGAIHVGDRILAINSVSLKGRPLSEAIHLLQVAGETVTLKIKKQLDRPLLPRQSGSLSEASDVDEDPPEALKGGLLTTHFSPAVPSVDSAVESWGSSATEGGFGGSGSYTPQVAVRSVTPQEWRSSRLKSSPPPLEPRRTSYTPGPTDESFPEEEEGDWEPPMSPAPGPAREEGFWRVLGEALEDLESCGQSELLRELEASIMTGTVQSVAVDGRPGSRPWRRSREVGTSPEDLQELLLPTPLEMHRVTLHKDPVRNDFGFSVSDGLLEKGVYVHTVRIDGPAQHGGLQPFDRLLQVNHVRTRDFDCCLAVPLLAEAGDILELVVSRNPLAQSRRTPGAPGPSSPQMI

Tissue specificity:Brain specific. Isoform 1 is expressed in the olfactory bulb, cortex and hippocampus and was also expressed at lower levels in thalamus, cerebellum and spinal cord. Isoform 3 is expressed in pyramidal cells of cortex and hippocampus, striatum, thalamus, hypothalamus, stellate cells of cerebellum, and brainstem. Isoform 2 and isoform 4 are expressed in cortex, hippocampus, thalamus, cerebellum, brainstem and spinal cord. In hippocampal neurons isoform 4 is found abundantly in spine structures. Isoform 2 is abundant in the cell body and also found in dendritic shafts. 3 s

Induction:

Developmental stage:Isoform 1 expression was relatively low early in development and increased postnatally, reaching a peak at P14. Isoform 3 is detected at low levels prior to P9, whereupon its expression increases, with the highest levels in the adult. 3 s

Protein families:GRIP2 family


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