P3H1_RAT   Q9R1J8


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UniProt:Q9R1J8

Recommended name:Prolyl 3-hydroxylase 1 Imported

EC number:EC:1.14.11.7

Alternative names:Leucine- and proline-enriched proteoglycan 1 1 Publication (Leprecan-1 1 Publication)

Cleaved into:

GeneID:114200

Gene names  (primary ):P3h1

Gene names  (synonym ):Lepre1 1 Publication

Gene names  (ORF ):

Length:728

Mass:82,390

Sequence:MVAVAAAAASRATAESEPEWNVAAPDLLYAEGTAAYARGDWPGVVLNMERALRSRAALRALRLRCRTRCATELPWAPDLDLGPASSLNHDPGAAALHDLRFFGALLRRAACLRRCLGPPSAHLLSEELDLEFNKRSPYNYLQVAYFKINKLEKAVAAAHTFFVGNPEHMEMRQNLDYYQTMSGVKEEDFKDLEAKPHMHEFRLGVRLYSEEKPLEAVPHLEAALQEYFVADEECRALCEGPYDYDGYNYLDYSADLFQAITDHYVQVLSCKQNCVTELASHPSREKPFEDFLPSHYNYLQFAYYNIGNYTQAIECAKTYLLFFPNDEVMSQNLAYYTAVLGEEEASSISPRENAQEYRHRSLLEKELLFFAYDIFGIPFVDPDSWTPEEVIPKRLQEKQKSERETAVRISQEIGNLMKEIETLVEEKTKESLDVSRLTREGGPLLYEGINLTMNSKVLNGSQRVVMDGVISDDECQELQRLTNAAATSGDGYRGQTSPHTPNEKFYGVTVLKALKLGQEGKVPLQSAHMYYNVTEKVRRVMESYFRLDTPLYFSYSHLVCRTAIEESQAERKDSSHPVHVDNCILNAESLVCIKEPPAYTFRDYSAILYLNGDFDGGNFYFTELDAKTVTAEVQPQCGRAVGFSSGTENPHGVKAVTRGQRCAIALWFTLDPRHSERDRVQADDLVKMLFSPEEVDLPQEQPLPDQQGSPKPGEESLSDRESQPKDEL

Tissue specificity:Expressed in basement membranes of cardiac muscle, skeletal muscle, central nervous system, intestinal tract, trachea, ear, skin, liver and kidney. In kidney, localizes to the glomerular basement membrane, mesangial matrix and Bowman's capsule of the nephron. In the renal parenchyma, expressed in the basement membranes of tubules and blood vessels. In the ear and trachea, localizes to the perimeter of resident chondrocytes in lacunae. 1

Induction:

Developmental stage:

Protein families:


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