S38A1_RAT Q9JM15
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UniProt:Q9JM15
Recommended name:Sodium-coupled neutral amino acid symporter 1 Curated
EC number:
Alternative names:
Cleaved into:
GeneID:170567
Gene names (primary ):Slc38a1
Gene names (synonym ):Ata1 2 Publications, Glnt, Sa2, Sat1 1 Publication, Snat1 1 Publication
Gene names (ORF ):
Length:485
Mass:53,846
Sequence:MMHFKSGLELTELQNMTVPEDDNVSNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKRKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAIKSLMGEEETFSAWYVDGRVLVVMVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCMNGEQNSTVSANVTDACTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYEKVQSDLLHKYQSTGDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFHLCRHVLVTIILLVIINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITNQDGDKNTQRIWAALFLALGVLFSLISIPLVIYDWACSSSNGEGH
Tissue specificity:Specifically expressed in brain with the highest levels in cerebellum and thalamus (at protein level) (PubMed:10660562). Expressed in glutamatergic, GABAergic and a subset of dopaminergic neurons of the substantia nigra and cholinergic motoneurons (at protein level) (PubMed:12684517). Also expressed by ependymal cells lining the ventricle (at protein level). Expression is also detected in spinal cord, heart, colon and placenta (PubMed:16023720). 6 s
Induction:Expressed at all stages examined including 17 dpc, 19 dpc, P2, P10 and P14. Expressed in neocortex, hippocampus and neuroepithelium at 17 dpc and more prominently expressed in striatum, hippocampus and cortex at postnatal days (at protein level). 1 Publication
Developmental stage:Up-regulated by forskolin in astrocytes. 1
Protein families: