ASAH2_RAT Q91XT9
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UniProt:Q91XT9
Recommended name：Neutral ceramidase Curated
EC number：EC:3.5.1.-
Alternative names：N-CDase; NCDase
Cleaved into：
GeneID：114104
Gene names (primary )：Asah2
Gene names (synonym )：
Gene names (ORF )：
Length：761
Mass：83,488
Sequence：MAKRTFSSLEAFLIFLLVMMTAITVALLTLLFVTSGTIENHKDSGNHWVSTTQGPTTTQSSPTTQTPTTQTPDLPPSQNFSGYYIGVGRADCTGQVSDINLMGYGKNGQNAQGLLTRLFSRAFILADPDGSNRMAFVSVELCMISQRLRLEVLKRLQSKYGSLYRRDNVILSATHTHSGPAGFFQYTLYILASEGFSNRTFQYIVSGIVKSIDIAHTNLKPGKVLINKGNVANVQINRSPSSYLQNPPSERARYSSDTDKEMVVLKLVDLNGEDLGLISWFAVHPVSMNNSNHLVNSDNMGYAAYLFEQEKNRGYLPGQGPFVAGFASSNLGDVSPNILGPHCVNTGESCDNDKSTCPSGGPSMCMASGPGQDMFESTHIIGRVIYQKAKELHASASQEVTGPVLTAHQWVNMTDVSVQLNATHTVKTCKAALGYSFAAGTIDGVSGLNITQGTTEGNLFWDTLRDQLLGKPSEEIIECQKPKPILIHTGELTKPHPWQPDIVDIQIVTLGSLAIAAIPGEFTTMSGRRLREAVKKEFALYGMKDMTVVIAGLSNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRALAKAIATDTVANMSSGPEPPFFKNLIGSLIPNIADRAPIGKQFGDVLQPAKPEYRVGEVVEVVFVGANPKNSAENQTHQTFLTVEKYEDSVANWQIMHNDASWETRFYWHKGVLGLSNATIHWHIPDTALPGVYRIRYFGHNRKQELLKPAVILAFEGISSPFEIVTT
Tissue specificity：Highly expressed in brain, kidney and heart (PubMed:11328816). Expressed at lower level in other tissues such as liver (PubMed:11328816). Expressed in intestine, kidney and liver (at protein level) (PubMed:11328816, PubMed:11330410). Localizes in the epithelia of the jejunum and ileum (PubMed:11330410). 2 s
Induction：
Developmental stage：By interleukin-1-beta in renal mesangial cells. 1
Protein families：