SNAT_RAT   Q64666


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UniProt:Q64666

Recommended name:Serotonin N-acetyltransferase

EC number:EC:2.3.1.87

Alternative names:Serotonin acetylase

Cleaved into:

GeneID:25120

Gene names  (primary ):Aanat

Gene names  (synonym ):Snat

Gene names  (ORF ):

Length:205

Mass:23,142

Sequence:MLSIHPLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCPLHLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESLTLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCENALVPFYEKFGFQAMGPCAITMGSLTFTELQCSLRCHTFLRRNSGC

Tissue specificity:Highly expressed at night in pinealocytes and in the retina. Expressed at very low levels in the hindbrain and midbrain. 2 s

Induction:

Developmental stage:Exhibits night/day variations with an up to 150-fold increased expression at night. Up-regulation is due to a large degree to the release of norepinephrine from nerve terminals in the pineal gland and cAMP signaling pathway. Down-regulated by light-induced proteasomal degradation. In the retina, 10-fold increased expression at night. 5 s

Protein families:


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