SNAT_RAT Q64666
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UniProt:Q64666
Recommended name:Serotonin N-acetyltransferase
EC number:EC:2.3.1.87
Alternative names:Serotonin acetylase
Cleaved into:
GeneID:25120
Gene names (primary ):Aanat
Gene names (synonym ):Snat
Gene names (ORF ):
Length:205
Mass:23,142
Sequence:MLSIHPLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCPLHLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESLTLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCENALVPFYEKFGFQAMGPCAITMGSLTFTELQCSLRCHTFLRRNSGC
Tissue specificity:Highly expressed at night in pinealocytes and in the retina. Expressed at very low levels in the hindbrain and midbrain. 2 s
Induction:
Developmental stage:Exhibits night/day variations with an up to 150-fold increased expression at night. Up-regulation is due to a large degree to the release of norepinephrine from nerve terminals in the pineal gland and cAMP signaling pathway. Down-regulated by light-induced proteasomal degradation. In the retina, 10-fold increased expression at night. 5 s
Protein families: