AIF1_RAT P55009
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UniProt:P55009
Recommended name:Allograft inflammatory factor 1
EC number:
Alternative names:Ionized calcium-binding adapter molecule 1 MRF-1 Microglia response factor
Cleaved into:
GeneID:29427
Gene names (primary ):Aif1
Gene names (synonym ):Iba1, Mrf1
Gene names (ORF ):
Length:147
Mass:16,827
Sequence:MSQSKDLQGGKAFGLLKAQQEERLDGINKHFLDDPKYSSDEDLQSKLEAFKTKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIREVSSGSEETFSYSDFLRMMLGKRSAILRMILMYEEKNKEHQKPTGPPAKKAISELP
Tissue specificity:Cardiac allograft, spleen and testis. Expressed by inflammatory cells (macrophages and neutrophils).
Induction:Expressed early and persistently in chronically rejecting cardiac allografts but is absent in cardiac syngrafts and host hearts. In the embryonic cerebellum, expression peaks at day 7.
Developmental stage:By interferon gamma.
Protein families: