AIF1_RAT   P55009


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UniProt:P55009

Recommended name:Allograft inflammatory factor 1

EC number:

Alternative names:Ionized calcium-binding adapter molecule 1 MRF-1 Microglia response factor

Cleaved into:

GeneID:29427

Gene names  (primary ):Aif1

Gene names  (synonym ):Iba1, Mrf1

Gene names  (ORF ):

Length:147

Mass:16,827

Sequence:MSQSKDLQGGKAFGLLKAQQEERLDGINKHFLDDPKYSSDEDLQSKLEAFKTKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIREVSSGSEETFSYSDFLRMMLGKRSAILRMILMYEEKNKEHQKPTGPPAKKAISELP

Tissue specificity:Cardiac allograft, spleen and testis. Expressed by inflammatory cells (macrophages and neutrophils).

Induction:Expressed early and persistently in chronically rejecting cardiac allografts but is absent in cardiac syngrafts and host hearts. In the embryonic cerebellum, expression peaks at day 7.

Developmental stage:By interferon gamma.

Protein families:


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