OXDA_RAT   O35078


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UniProt:O35078

Recommended name:D-amino-acid oxidase

EC number:EC:1.4.3.3

Alternative names:DAAO; DAMOX; DAO

Cleaved into:

GeneID:114027

Gene names  (primary ):Dao

Gene names  (synonym ):Dao1

Gene names  (ORF ):

Length:346

Mass:38,820

Sequence:MRVAVIGAGVIGLSTALCIHERYHPAQPLHMKIYADRFTPFTTSDVAAGLWQPYLSDPSNPQEAEWNQQTFDHLQSCLHSPNAEKMGLALISGYNLFRDEVPDPFWKSTVLGFRKLTPSELDMFPDYSYGWFNTSLLLEGKSYLSWLTERLTERGVKFIHRKVASFEEVVRGGVDVIINCTGVWAGALQADASLQPGRGQIIQVEAPWIKHFILTHDPSLGIYNSPYIIPGSKTVTLGGVFQLGNWSELNSVHDHNTIWKSCCQLEPTLKNARIMGELTGFRPVRPQVRLERERLRFGSSSAEVIHNYGHGGYGLTIHWGCAMEAANLFGKILEEKNLSRMPPSHL

Tissue specificity:Expressed in the cerebellum, liver and proximal tubules of the renal cortex (at protein level) (PubMed:17880399, PubMed:20564560, PubMed:21700703, PubMed:26961980, PubMed:2896644). Absent from spleen (at protein level) (PubMed:21700703). 5 s

Induction:In the liver and kidney, progressively increases during postnatal stages (at protein level). 1 Publication

Developmental stage:Increased in pups born to mothers fed D-alanine during pregnancy and suckling; not induced when mothers fed D-aspartate (PubMed:7903300). Not induced further in the cerebellum following two weeks of intraperitoneal injections of the antipsychotic haloperidol (PubMed:17880399). 2 s

Protein families:


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