EGLN3_RAT Q62630
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UniProt:Q62630
Recommended name:Prolyl hydroxylase EGLN3 Curated
EC number:EC:1.14.11.-
Alternative names:Egl nine homolog 3 (EC:1.14.11.29 By Similarity) . EC:1.14.11.29 (UniProtKB | ENZYME | Rhea) By Similarity Hypoxia-inducible factor prolyl hydroxylase 3 (HIF-PH3; HIF-prolyl hydroxylase 3; HPH-3) Prolyl hydroxylase domain-containing protein 3 (PHD3) SM-20 2 Publications
Cleaved into:
GeneID:54702
Gene names (primary ):Egln3
Gene names (synonym ):Sm20 2 Publications
Gene names (ORF ):
Length:239
Mass:27,242
Sequence:MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHYNGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAINFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGVLRIFPEGKSFVADVEPIFDRLLFSWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALAKD
Tissue specificity:Highly expressed in vascular smooth muscle. Moderately expressed in esophagus, stomach, small bowel and aorta. Low levels in tail and kidney. Expression also in pheochromocytoma cell line PC-12. 4 s
Induction:
Developmental stage:By PDGF and angiotensin II in aortic smooth muscle cells. By deprivation of NGF in neuronal cell cultures. Induced during coronary heart ligation. 4 s
Protein families: