FTO_RAT   Q2A121


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UniProt:Q2A121

Recommended name:Alpha-ketoglutarate-dependent dioxygenase FTO Curated

EC number:

Alternative names:

Cleaved into:

GeneID:291905

Gene names  (primary ):Fto 1 Publication

Gene names  (synonym ):

Gene names  (ORF ):

Length:502

Mass:57,972

Sequence:MKRVQTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLVFREAGSIPEELHKEVPEAFLTLHKHGCLFRDLVRIQGKDVLTPVSRILIGDPGCTYKYLNTRLFTVPWPVKGCTINYTEAEIAAACQTFLKLNDYLQVETIQALEELAIKEKANEDAVPLCMAEFPRAGVGPSCDDEVDLKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGSEDESDDESSFEGRDPDTWHVGFKISWDIETPGLTIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVLNDSDNGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKICTDWWCEPMTQLEGLWKKMESVTNAVLREVKREGLSVEQRSEILSAVLIPLTMRQNLRKEWHARCQARVVRTLPAQQKPDCRPYWEKDDPSMPLPFDLTDVVSEIRSQLLEARS

Tissue specificity:Ubiquitous (PubMed:17143547, PubMed:18218688). Highly expressed in teeth and weakly in bone (PubMed:17143547). 2 s

Induction:

Developmental stage:Up-regulated in the hypothalamus after 48 hours fasting. 1

Protein families:fto family