FTO_RAT Q2A121
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UniProt:Q2A121
Recommended name:Alpha-ketoglutarate-dependent dioxygenase FTO Curated
EC number:
Alternative names:
Cleaved into:
GeneID:291905
Gene names (primary ):Fto 1 Publication
Gene names (synonym ):
Gene names (ORF ):
Length:502
Mass:57,972
Sequence:MKRVQTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLVFREAGSIPEELHKEVPEAFLTLHKHGCLFRDLVRIQGKDVLTPVSRILIGDPGCTYKYLNTRLFTVPWPVKGCTINYTEAEIAAACQTFLKLNDYLQVETIQALEELAIKEKANEDAVPLCMAEFPRAGVGPSCDDEVDLKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGSEDESDDESSFEGRDPDTWHVGFKISWDIETPGLTIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVLNDSDNGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKICTDWWCEPMTQLEGLWKKMESVTNAVLREVKREGLSVEQRSEILSAVLIPLTMRQNLRKEWHARCQARVVRTLPAQQKPDCRPYWEKDDPSMPLPFDLTDVVSEIRSQLLEARS
Tissue specificity:Ubiquitous (PubMed:17143547, PubMed:18218688). Highly expressed in teeth and weakly in bone (PubMed:17143547). 2 s
Induction:
Developmental stage:Up-regulated in the hypothalamus after 48 hours fasting. 1
Protein families:fto family