HMGCL_RAT   P97519


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UniProt:P97519

Recommended name:Hydroxymethylglutaryl-CoA lyase, mitochondrial

EC number:EC:4.1.3.4

Alternative names:HL; HMG-CoA lyase

Cleaved into:

GeneID:79238

Gene names  (primary ):Hmgcl

Gene names  (synonym ):

Gene names  (ORF ):

Length:325

Mass:34,192

Sequence:MATVRKAFPQRLVGLASLRAASTSSMGTLPKRVKIVEVGPRDGLQNEKSIVPTPVKIKLIDMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNMKGFEEAVAAGAKEVSIFGAASELFTRKNVNCSIEESFQRFDGVMQAARAASISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAVLHEVPVAALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLGGCPYAKGASGNLATEDLVYMLTGLGIHTGVNLQKLLEAGDFICQALNRKTSSKVAQATCKL

Tissue specificity:In suckling rat, highest levels in liver and in intestine. Lower levels in heart, kidney and cerebellum. Weak expression in brain cortex, medulla and midbrain. Levels decrease slightly during weaning. 1

Induction:

Developmental stage:

Protein families:


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