GSH1_RAT   P19468


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UniProt:P19468

Recommended name:Glutamate--cysteine ligase catalytic subunit Curated

EC number:EC:6.3.2.2

Alternative names:GCS heavy chain Gamma-ECS Gamma-glutamylcysteine synthetase

Cleaved into:

GeneID:25283

Gene names  (primary ):Gclc

Gene names  (synonym ):Glclc

Gene names  (ORF ):

Length:637

Mass:72,619

Sequence:MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDHENRKVQLLLNGGDVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEDNMRKRRKEATSVLGEHQALCTITSFPRLGCPGFTLPEHRPNPEEGGASKSLFFPDEAINKHPRFGTLTRNIRHRRGEKVVINVPIFKDKNTPSPFVETFPEDEEASKASKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVISASVDDRTREERGLEPLKNNRFKISKSRYDSIDSYLSKCGEKYNDIDLTIDTEIYEQLLEEGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQERDAVLQGMFYFRKDICKGGNAVVDGCSKAQTSSEPSAEEYTLMSIDTIINGKEGVFPGLIPILNSYLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEINYSLILKCNQIANELCECPELLGSGFRKAKYSGGKSDPSD

Tissue specificity:Most abundant in kidney. Also found in liver and testis.

Induction:

Developmental stage:

Protein families:


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