UCHL1_HUMAN P09936
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UniProt:P09936
Recommended name：Ubiquitin carboxyl-terminal hydrolase isozyme L1
EC number：EC:3.4.19.12
Alternative names：(UCH-L1) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)
Cleaved into：
GeneID：7345
Gene names (primary )：UCHL1
Gene names (synonym )：
Gene names (ORF )：
Length：223
Mass：24824
Sequence：MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA
Tissue specificity：Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients. {ECO:0000269|PubMed:14722078, ECO:0000269|PubMed:9790970}.
Induction：
Developmental stage：
Protein families：Peptidase C12 family