SAPC2_HUMAN   Q86UD0


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UniProt:Q86UD0

Recommended name:Suppressor APC domain-containing protein 2

EC number:

Alternative names:(Tumor specificity and mitosis phase-dependent expression protein) (TS/MDEP) (p42.3)

Cleaved into:

GeneID:89958

Gene names  (primary ):SAPCD2

Gene names  (synonym ):C9orf140

Gene names  (ORF ):

Length:394

Mass:42637

Sequence:MAGAAMAERGRVPPPAPAPSTEGLPRAFLQSLRTLFDILDDRRRGCVHLREIESRWQGTDARELPRGVLEGLRQVAPASGYLTFERFVAGLRTSLLSADGGPRDPTRAPARPGDQPPPPPQRLVFAPADEPRTVLERKPLPLGVRAPLAGPSAAARSPEQLCAPAEAAPCPAEPERSQSAALEPSSSADAGAVACRALEADSGDARRAPRARGERRRHTIASGVDCGLLKQMKELEQEKEVLLQGLEMMARGRDWYQQQLQRVQERQRRLGQSRASADFGAAGSPRPLGRLLPKVQEVARCLGELLAAACASRALPPSSSGPPCPALTSTSPPVWQQQTILMLKEQNRLLTQEVTEKSERITQLEQEKSALIKQLFEARALSQQDGGPLDSTFI

Tissue specificity:Expressed in 5-month-old fetal tissues, including stomach, intestine, colon, liver, brain, lung, heart, spleen and kidney (PubMed:17525738). Undetectable in non-cancerous adult tissues (PubMed:17525738). Expressed in many primary gastric carcinoma, but almost not in adjacent normal mucosa (PubMed:17525738). Expressed preferentially in M and G1 phases, compared to S and G2 phases (PubMed:17525738). Expression is up-regulated in hepatocellular carcinoma (HCC) and colorectal cancer (CRC) tissues (at protein level) (PubMed:23704824). {ECO:0000269|PubMed:17525738, ECO:0000269|PubMed:23704824}.

Induction:

Developmental stage:

Protein families:


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