PTGR1_HUMAN Q14914
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UniProt:Q14914
Recommended name:Prostaglandin reductase 1
EC number:EC:1.3.1.48
Alternative names:(PRG-1) (15-oxoprostaglandin 13-reductase) (Dithiolethione-inducible gene 1 protein) (D3T-inducible gene 1 protein) (DIG-1) (Leukotriene B4 12-hydroxydehydrogenase) (NAD(P)H-dependent alkenal/one oxidoreductase)
Cleaved into:
GeneID:22949
Gene names (primary ):PTGR1
Gene names (synonym ):LTB4DH
Gene names (ORF ):
Length:329
Mass:35870
Sequence:MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKEYIIEGFENMPAAFMGMLKGDNLGKTIVKA
Tissue specificity:High expression in the kidney, liver, and intestine but not in leukocytes. {ECO:0000269|PubMed:8576264}.
Induction:
Developmental stage:
Protein families:NADP-dependent oxidoreductase L4BD family