S22A6_HUMAN   Q4U2R8


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UniProt:Q4U2R8

Recommended name:Solute carrier family 22 member 6

EC number:

Alternative names:(Organic anion transporter 1) (hOAT1) (PAH transporter) (hPAHT) (Renal organic anion transporter 1) (hROAT1)

Cleaved into:

GeneID:9356

Gene names  (primary ):SLC22A6

Gene names  (synonym ):OAT1 PAHT

Gene names  (ORF ):

Length:563

Mass:61816

Sequence:MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRWAPTQKEAGIYPRKGKQTRQQQEHQKYMVPLQASAQEKNGL

Tissue specificity:Strongly expressed in kidney and to a lower extent in liver, skeletal muscle, brain and placenta. Found at the basolateral membrane of the proximal tubule. {ECO:0000269|PubMed:10049739, ECO:0000269|PubMed:10462545, ECO:0000269|PubMed:10964714, ECO:0000269|PubMed:9887087, ECO:0000269|PubMed:9950961}.

Induction:

Developmental stage:

Protein families:Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family


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