MCH_HUMAN P20382
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UniProt:P20382
Recommended name：Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid
EC number：
Alternative names：(NGE) (Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine(NEI) (Neuropeptide E-I); Melanin-concentrating hormone(MCH)]
Cleaved into：Neuropeptide-glycine-glutamic acid (NGE) (Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine (NEI) (Neuropeptide E-I); Melanin-concentrating hormone (MCH)
GeneID：5367
Gene names (primary )：PMCH
Gene names (synonym )：MCH
Gene names (ORF )：
Length：165
Mass：18679
Sequence：MAKMNLSSYILILTFSLFSQGILLSASKSIRNLDDDMVFNTFRLGKGFQKEDTAEKSVIAPSLEQYKNDESSFMNEEENKVSKNTGSKHNFLNHGLPLNLAIKPYLALKGSVAFPAENGVQNTESTQEKREIGDEENSAKFPIGRRDFDMLRCMLGRVYRPCWQV
Tissue specificity：Predominantly expressed in lateral hypothalamus, also detected in pallidum, neocortex and cerebellum. Also found in thymus, brown adipose tissue, duodenum and testis (spermatogonia, early spermatocytes and Sertoli cells). No expression in peripheral blood. In brain exclusively mature MCH and NEI peptides are present. In peripheral tissues a large product, encompassing the NEI and MCH domains of the precursor, is found predominantly. {ECO:0000269|PubMed:9191099}.
Induction：
Developmental stage：
Protein families：Melanin-concentrating hormone family