NDKA_HUMAN   P15531


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UniProt:P15531

Recommended name:Nucleoside diphosphate kinase A

EC number:EC:2.7.4.6

Alternative names:(NDK A) (NDP kinase A) (Granzyme A-activated DNase) (GAAD) (Metastasis inhibition factor nm23) (NM23-H1) (Tumor metastatic process-associated protein)

Cleaved into:

GeneID:4830

Gene names  (primary ):NME1

Gene names  (synonym ):NDPKA NM23

Gene names  (ORF ):

Length:152

Mass:17149

Sequence:MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE

Tissue specificity:Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. {ECO:0000269|PubMed:10512675, ECO:0000269|PubMed:12601555, ECO:0000269|PubMed:16442775}.

Induction:

Developmental stage:

Protein families:NDK family


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