MP2K4_HUMAN P45985
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UniProt:P45985
Recommended name：Dual specificity mitogen-activated protein kinase kinase 4
EC number：EC:2.7.12.2
Alternative names：(MAP kinase kinase 4) (MAPKK 4) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)
Cleaved into：
GeneID：6416
Gene names (primary )：MAP2K4
Gene names (synonym )：JNKK1 MEK4 MKK4 PRKMK4 SEK1 SERK1 SKK1
Gene names (ORF )：
Length：399
Mass：44288
Sequence：MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
Tissue specificity：Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
Induction：
Developmental stage：
Protein families：Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily