MP2K3_HUMAN P46734
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UniProt:P46734
Recommended name:Dual specificity mitogen-activated protein kinase kinase 3
EC number:EC:2.7.12.2
Alternative names:(MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)
Cleaved into:
GeneID:5606
Gene names (primary ):MAP2K3
Gene names (synonym ):MEK3 MKK3 PRKMK3 SKK2
Gene names (ORF ):
Length:347
Mass:39318
Sequence:MESPASSQPASMPQSKGKSKRKKDLRISCMSKPPAPNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
Tissue specificity:Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
Induction:
Developmental stage:
Protein families:Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily