MP2K3_HUMAN   P46734


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UniProt:P46734

Recommended name:Dual specificity mitogen-activated protein kinase kinase 3

EC number:EC:2.7.12.2

Alternative names:(MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)

Cleaved into:

GeneID:5606

Gene names  (primary ):MAP2K3

Gene names  (synonym ):MEK3 MKK3 PRKMK3 SKK2

Gene names  (ORF ):

Length:347

Mass:39318

Sequence:MESPASSQPASMPQSKGKSKRKKDLRISCMSKPPAPNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS

Tissue specificity:Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.

Induction:

Developmental stage:

Protein families:Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily


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