RAE1E_HUMAN   Q8TD07


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UniProt:Q8TD07

Recommended name:Retinoic acid early transcript 1E

EC number:

Alternative names:(Lymphocyte effector toxicity activation ligand) (NKG2D ligand 4) (N2DL-4) (NKG2DL4) (RAE-1-like transcript 4) (UL16-binding protein 4)

Cleaved into:

GeneID:135250

Gene names  (primary ):RAET1E

Gene names  (synonym ):LETAL N2DL4 ULBP4

Gene names  (ORF ):UNQ1867/PRO4303

Length:263

Mass:30122

Sequence:MRRISLTSSPVRLLLFLLLLLIALEIMVGGHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPSTLQVEMFCQREAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSSSSLPDRWIILGAFILLVLMGIVLICVWWQNGEWQAGLWPLRTS

Tissue specificity:Predominantly expressed in the skin, but also expressed in testis and trachea. Up-regulated in tumor cells of different origins. Expression progressively decreased after treatment of tumor cells with retinoic acid. {ECO:0000269|PubMed:12732206, ECO:0000269|PubMed:14508119}.

Induction:

Developmental stage:

Protein families:MHC class I family


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