LTC4S_HUMAN   Q16873


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UniProt:Q16873

Recommended name:Leukotriene C4 synthase

EC number:EC:4.4.1.20

Alternative names:(LTC4 synthase) (Glutathione S-transferase LTC4) (Leukotriene-C(4) synthase) (Leukotriene-C4 synthase)

Cleaved into:

GeneID:4056

Gene names  (primary ):LTC4S

Gene names  (synonym ):

Gene names  (ORF ):

Length:150

Mass:16567

Sequence:MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA

Tissue specificity:Detected in lung, platelets and the myelogenous leukemia cell line KG-1 (at protein level). LTC4S activity is present in eosinophils, basophils, mast cells, certain phagocytic mononuclear cells, endothelial cells, vascular smooth muscle cells and platelets. {ECO:0000269|PubMed:7599836}.

Induction:

Developmental stage:

Protein families:MAPEG family


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