KERA_HUMAN   O60938


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UniProt:O60938

Recommended name:Keratocan

EC number:

Alternative names:(KTN) (Keratan sulfate proteoglycan keratocan)

Cleaved into:

GeneID:11081

Gene names  (primary ):KERA

Gene names  (synonym ):SLRR2B

Gene names  (ORF ):

Length:352

Mass:40509

Sequence:MAGTICFIMWVLFITDTVWSRSVRQVYEVHDSDDWTIHDFECPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRLLQAVII

Tissue specificity:Cornea (at protein level) (PubMed:10802664, PubMed:11683372). Increased expression in the stroma of keratoconus corneas (PubMed:11683372). Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen (PubMed:10802664). {ECO:0000269|PubMed:10802664, ECO:0000269|PubMed:11683372}.

Induction:

Developmental stage:

Protein families:Small leucine-rich proteoglycan (SLRP) family, SLRP class II subfamily


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