HOT_HUMAN Q8IWW8
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UniProt:Q8IWW8
Recommended name:Hydroxyacid-oxoacid transhydrogenase, mitochondrial
EC number:EC:1.1.99.24
Alternative names:(HOT) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase)
Cleaved into:
GeneID:137872
Gene names (primary ):ADHFE1
Gene names (synonym ):
Gene names (ORF ):HMFT2263
Length:467
Mass:50308
Sequence:MAAAARARVAYLLRQLQRAACQCPTHSHTYSQAPGLSPSGKTTDYAFEMAVSNIRYGAAVTKEVGMDLKNMGAKNVCLMTDKNLSKLPPVQVAMDSLVKNGIPFTVYDNVRVEPTDSSFMEAIEFAQKGAFDAYVAVGGGSTMDTCKAANLYASSPHSDFLDYVSAPIGKGKPVSVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKIGITSRAIKPTLGLIDPLHTLHMPARVVANSGFDVLCHALESYTTLPYHLRSPCPSNPITRPAYQGSNPISDIWAIHALRIVAKYLKRAVRNPDDLEARSHMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKMYKAKDYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLEMAEILGADTRTARIQDAGLVLADTLRKFLFDLDVDDGLAAVGYSKADIPALVKGTLPQERVTKLAPCPQSEEDLAALFEASMKLY
Tissue specificity:Only expressed in adult liver. {ECO:0000269|PubMed:12592711}.
Induction:
Developmental stage:
Protein families:Iron-containing alcohol dehydrogenase family, Hydroxyacid-oxoacid transhydrogenase subfamily