FA11_HUMAN P03951
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UniProt:P03951
Recommended name：Coagulation factor XI
EC number：EC:3.4.21.27
Alternative names：(FXI) (Plasma thromboplastin antecedent) (PTA)
Cleaved into：Coagulation factor XIa heavy chain; Coagulation factor XIa light chain
GeneID：2160
Gene names (primary )：F11
Gene names (synonym )：
Gene names (ORF )：
Length：625
Mass：70109
Sequence：MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV
Tissue specificity：Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.
Induction：
Developmental stage：
Protein families：Peptidase S1 family, Plasma kallikrein subfamily