ELF5_HUMAN   Q9UKW6


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UniProt:Q9UKW6

Recommended name:ETS-related transcription factor Elf-5

EC number:

Alternative names:(E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)

Cleaved into:

GeneID:2001

Gene names  (primary ):ELF5

Gene names  (synonym ):ESE2

Gene names  (ORF ):

Length:265

Mass:31263

Sequence:MPSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVHPEYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYFILQNIRTQGYSFFNDAEESKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVDRRLVYKFGKNAHGWQEDKL

Tissue specificity:Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tissues. In the kidney, only isoform 1 was expressed, while prostate expressed both isoforms, with levels of isoform 2 being higher. Expression is up-regulated during keratinocyte differentiation. Several epithelial carcinoma cell lines showed lack of expression. {ECO:0000269|PubMed:10506207, ECO:0000269|PubMed:9840936}.

Induction:

Developmental stage:

Protein families:ETS family


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